Reference no: EM133765393

Question

I would like to rate a nurse manager proficient based off of the following: "Quality: Improve required HSMP Nursing documentaiton compliance by 2% (Aligns with OSHW Strategic Priority: Data and Accountability and Organizational Blueprint of Accountability as well as lagging indicators for increasing student attendance) "

A 66-year-old man with 35 years of smoking history and family history of coronary heart disease take atorvastatin to reduce cholesterol levels and aspirin to reduce risk of coronary artery occlusion suddenly felt tightness in his chest which rapidly became so painful, and the pain radiate down his left arm. It was determined that the man was having anterior myocardial infarction. Since he has no relative contraindication to thrombolytic therapy including high blood pressure, stroke or recent surgery, the physician initiate treatment with both a thrombolytic agent, tissue-type plasminogen activator (tPA) and an anticoagulant heparin. Because of their low therapeutic index (TI), improper dosing of both drugs could have disastrous consequences such as hemorrhage and death, he was closely monitored, and the pharmacological effect of heparin was measured regularly by testing the partial thromboplastin time (PTT). The symptoms resolved in few hours and he was monitored for some days and discharged with the following medications' atorvastatin, aspirin, atenolol, lisinopril and clopidogrel for secondary prevention of myocardial infarction. How does the interaction of a drug with its receptor determine the potency and efficacy of the drug? Why does the fact that a drug has a low therapeutic index mean that the.