History of atopy and mild lung disease

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Reference no: EM133803764

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This is a 19-year-old female with a history of atopy and mild lung disease secondary to cystic fibrosis presented with a 3-week history of increased sputum production, dyspnea, and wheezing. I last saw this patient 6 months ago. The patient's genotype was Delta F508/2789 5 G-T. She was pancreatic sufficient and had never required therapy with intravenous antibiotics. The patient had previously undergone allergy testing and had received immunotherapy for allergies to pet dander. She attributed this recent illness to an exacerbation of her allergies as a result of exposure to a dog while visiting relatives. PAST HISTORY: Pancreatitis at age 15 requiring hospitalization, and major depression for which she had received treatment with sertraline in the past. PHYSICAL EXAM: Significant for crackles in the midlung fields, and a prolonged expiratory phase with diffuse wheezing. LAB: WBC 14,400 with 0.9% eosinophils and an elevated serum IgE level of 2840 IU. Spirometry performed prebronchodilator revealed an FEV1 of 3.15 liters (69% of predicted). Post bronchodilator the FEV1 increased to 3.55 liters (77% of predicted). Chest x-ray, single view, frontal, revealed a patchy infiltrate in the superior segment of the right lower lobe. On the basis of this presentation, a further evaluation.

Reference no: EM133803764

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