History of angioedema-anaphylaxis and atopy

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Which of the following is the most common cause of toxic epidermal necrolysis (TEN)? A 55-year-old postmenopausal woman presents to you for evaluation after she noticed a diffuse, pruritic rash that started without provocation 1 day earlier (see Figure). Figure. During today's visit, she tells you that the rash is starting to improve. She notes no lip or tongue swelling and has no difficulty breathing or chest pain. The patient notes no new occupational, pet, soap, or detergent exposures, and no new medications, no recent travel, and no other environmental changes. She does not have any known allergies, does not take any medications, and has no history of angioedema, anaphylaxis, atopy, or prior episodes of this kind. Her vital signs are within normal limits. What is the most likely diagnosis?

Reference no: EM133721859

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