Hdac inhibitors and chemotherapy

Reference no: EM131002459

A tumor was treated with HDAC inhibitors and chemotherapy. When cells from the treated tumor were transplanted into another mouse, the treated tumor cells gave rise to tumors in the second mouse more efficiently. Why might this have happened? What is the mechanism? How would you test your mechanism? (Help for any of these questions would be greatly appreciated!

Reference no: EM131002459

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