User Account

All Pages

Genetic mutations exercise

Assignment Help Biology
Reference no: EM131922665

Genetic Mutations Exercise

Instructions: Below you are given an imaginary wildtype sense strand (coding strand) of DNA and the corresponding mature mRNA sequence with its corresponding protein sequence. Five mutant DNA sense strands are presented. For each mutant DNA strand (mutant 2-5), write the mRNA strand, the protein sequence, and an explanation of the type(s) of mutation represented, including the impact on protein synthesis. I have completed the first mutant as an example. I will post the answers after the assignment has been submitted. This is a required homework activity worth 5 points.

Wildtype sense strand sequence: ATG-TCA-CCC-GCG-CAG-GAA-GGA

(Upper case letters denote coding sequence of the DNA)

Mature mRNA sequence: AUG-UCA-CCC-GCG-CAG-GAA-GGA

Protein sequence: methionine-serine-proline-alanine-glutamine-glutamic acid-glycine

Mutant 1:                                                            ATG-TGA-CCC-GCG-CAG-GAA-GGA

mRNA:                                                                  AUG-UGA-CCC-GCG-CAG-GAA-GGA

Protein:                                                                 methionine-stop

Mutation:                                                            The fifth base is changed from a C to a G. This is a point mutation (and a base substitution). The mutation causes a nonsense mutation because a codon for serine is replaced by a stop codon, resulting in a truncated protein.

Mutant 2:                                                            ATG-TCA-ACC-GCG-CAG-GAA-GGA

mRNA:                                                                  AUG-UCA-ACC-GCG-CAG-GAA-GGA

Protein:                                                                 Methionine-Serine-Threonine-Alanine-Glutamine-Glutamic acid-Glycine

Mutation:                                                            

Mutant 3:                                                            ATG-CAT-TCA-CCC-GCG-CAG-GAA-GGA

mRNA:                                                                  AUG-CAT-UCA-CCC-GCG-CAG-GAA-GGA

Protein:                                                                 Methionine-

Mutation:

Reference no: EM131922665

Questions Cloud

How many pairs of electrons are stripped from substrate : How many molecules of FAD are reduced? How many pairs of electrons are stripped from substrate?
The principles of universal design for learning : Provides the opportunity for you to apply the principles of universal design for learning (UDL) in the design of instruction and assessment.
Diabetes mellitus to develop ketoacidosis : What are some triggers that may cause a patient with reasonably well controlled type 1 diabetes mellitus to develop ketoacidosis?
Make the necessary journal entries to record the exchange : Assume that the exchange of assets has commercial substance. Make the necessary journal entries to record the exchange for both parties
Genetic mutations exercise : Below you are given an imaginary wildtype sense strand (coding strand) of DNA and the corresponding mature mRNA
How can you be a resource for your leader : How can you be a resource for your leader? How can you help the leader be a good leader? How can you build a relationship with the leader?
Discuss about the adverse childhood events : Adverse childhood events (ACE) or traumatic events experienced by a child, have long-term medical and psychological consequences.
How is that a trained athlete could die of dehydration : How is that a trained athlete could die of dehydration? Please use physiology explanations in your response
What is the size of the object in cm : If the field of view is 450 um wide and an object is about 1/5 the size of the field of view, what is the size of the object in cm?

Reviews

Write a Review

Biology Questions & Answers

  Describe the process of carbon dioxide transportation

Describe the process of Carbon dioxide transportation in the blood including the carbonic acid-bicarbonate buffer system and the chloride shift.

  How are histones involved in regulation

How are histones involved in regulation of eukaryotic gene regulation? Be sure to consider the dynamic nature of this regulation so you should discuss how genes can be turned on or off depending on the chromatin. Also, indicate how chromatin is us..

  Discuss the methods of diagnosis

Discuss the methods of diagnosis of one disease of low cell count like anaemia.

  What is the structure of the dimer of benzoic acid

What is the structure of the dimer of benzoic acid in toluene? Why does it not form in water? (Explain.) Why is phenolphthalein

  What are the geochemcial and microbiological

What are the geochemcial and microbiological differences between surface, shallow subsurface and deep subsurface habitat?

  Are we in the post-antibiotic era

Please read the article titled, "Resistance to Antibiotics: Are We in the Post-Antibiotic Era?" Please provide your thoughts on drug resistance, and explain what you thought was an important fact from this article

  Contains sodium hydrogen carbonate

Suppose a household product label says it contains sodium hydrogen carbonate (sodium bicarbonate). How would you test this material for the presence of sodium

  What is the difference between the chemical formula

What is the difference between the chemical formula and the condensed formula of organic compounds? What information does each provide?

  Research potential mechanisms

Speculate on and/or research potential mechanisms which would afford the improved processing. Speculate on and/or research potential mechanisms.

  Dilution of the entire culture

suppose your professor handed you a test tube with 2.0mL of an E.coli broth culture in it and told you to make a 10^-1 dilution of the entire culture. Explain how you would do this. Show your calculations

  What about whale fins compared to fish fins

What about whale fins compared to fish fins?

  Albinism is a recessive disease

Albinism is a recessive disease (single gene, 2 alleles).What is the ratio of heterozygous carriers of albinism to homozygous recessive individuals (i.e. people with albinism)?

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

Submit Assignment

Academics

Major Subjects

Majors

Get In Touch

whatsapp: +1-415-670-9521

Phone: +1-415-670-9521

Email: [email protected]

TERMS & POLICIES

HELP & SUPPORT

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd