Full sickle cell anemia

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During the summer of 2013 it was determined that a small Nigerian village had a population of 2,089 people. The per capita incidence of people born with sickle-cell anemia (an autosomal recessive disease) in this village, was the highest in the country with 324 people in this population having the condition. The people with sickle-cell anemia require extensive therapy for this otherwise lethal disease. However, a heterozygous advantage exists with carriers of the sickle-cell allele providing resistance to malaria, a lethal disease that is highly prevalent in this village. People heterozygous for the sickle cell allele produce an environment in some of their blood cells that is toxic to the parasite that causes malaria. How many people (to the nearest whole person) are expected to be resistant to malaria but NOT have full sickle cell anemia?

Reference no: EM133307476

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