Find the total sample size required

Reference no: EM13953441

Ovarian cancer is the fourth most common cause of cancer deaths in women. Approximately 75% of patients present with an advanced stage, and because of this, only a minority of patients will have surgically curable localized disease, and systematic chemotherapy has become the primary treatment modality. A randomized phase III trial is considered to compare paclitaxel-carboplatin versus docetaxel- carboplatin as first-line chemotherapy in stage IV epithelial ovarian cancer. Suppose that we plan to use a statistical test at the two-sided 5% level of significance and the study is designed to have 80% power to detect the alternative hypothesis that the two-year survival rates in the paclitaxel and docetaxel arms are 40% and 50%, respectively. Find the total sample size required.

Reference no: EM13953441

Questions Cloud

Calculate total sample size needed using a two-sided test : Find the total sample size needed using a two-sided test at the 0.05 level of significance and a statistical power of 80% to detect the alternative hypothesis that the two-year relapse rates in the placebo and the new drug arms are 60% and 40%, re..

Effects that inventory transactions : Explain the effects that inventory transactions have on the statement of cash flows.

Write a single side chat for command line interface : Write a socket based single side chat for command line interface. The client will keep typing messages and server will print it as soon as the client hit enter key. Terminate the program when client hit dot(.).

In psychology using the theories of piaget : In Psychology Using the theories of Piaget, LaBouvie-Vief, and Denney (plus the ideas of fluid and crystallized intelligence), explain changes in cognitive functioning in adolescence, emerging adulthood, and middle adulthood.

Find the total sample size required : Suppose that we plan to use a statistical test at the two-sided 5% level of significance and the study is designed to have 80% power to detect the alternative hypothesis that the two-year survival rates in the paclitaxel and docetaxel arms are 40%..

Explain how horizontal motioncan be uniform : Explain how horizontal motioncan be uniform while vertical motion is accelerated.How will projectile motion be affected when dragdue to air resistance is taken into consideration?

Find the total sample size needed using a two-sided test : The five-year disease-free survival rate for women receiving CEF alone as adjuvant therapy was estimated at about 60%, and it is hypothesized that the newly formed regimen would improve that rate from 60% to 70%. Find the total sample size needed ..

List all outcomes in the sample space : You toss two dice and compute the "difference," which you will define to be the larger top number minus the smaller top number if the numbers are different, and 0 if the numbers are the same.

Force act on the yo-yo : Suppose you whirl a yo-yo about your head in ahorizontal circle.a. In what direction must a force act on the yo-yo? b. What exerts the force?

User Account

All Pages