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Insulin is released from pancreatic b cells when blood glucose levels increase and glucagon is released from pancreatic a cells when blood glucose levels decrease. Blood glucose concentration is tightly controlled and at the basic level it appears that glucose binds to GLUT2 receptors on b cells increasing the concentration of ATP because of the increased concentration of glucose in these cells. The increase in ATP decreases potassium concentrations and calcium channels are opened leading to insulin secretion. There are, however, a number of other insulin/glucagon regulators such as amino acids,catecholamines, insulin, neurotransmitters and free fatty acids. Consequently the search for causes of obesity requires careful focus and much of current research focuses on G Protein Coupled Receptors.Which of the following is not of special interest to those studying GPCR and their involvement in diabetes and obesity?
a. allelic (SNP) differences in the extracellular domain of GPCRs between obese and controls
b. classes of GPCRs found in target tissues thought to be associated with obesity
c. a subunits associated with G proteins in tissues thought to be associated with obesity
d. the role of uncoupling mitochondrial membrane proteins in target tissues
e. the binding of molecules other than glucose to GPCRs on target tissues
In lecture we discussed plants transitioning from water to land, thus pretend you were this plant clearly identify at least theree things you need to survive on land.
Trace path from the femoral vein in a healthy female to the lower lobe of the right lung via the right pulmonary artery. Explain all major structures on the way.
Inversion or Translocation heterozygotes have difficultyin producing gametes that function properly. Is there a way that an Inversion heterozygote could manufacture functional gametes?
What is estimated density of firs in the forest. Why then is the gene called Dorsal, and not, for instance, Ventral.
Bone marrow contains at least three populations of stem cells. How do you isolate HSCs from human bone marrow separately from the other two then and discuss the structural and functional changes of Ichemic stroke.
in what direction does polymerization of RNA occur.
Is it harder to prove a hypothesis than to disprove it? Suppose you wanted to establish that cheetahs are fastest land animals, and suppose you've the ability to clock any animal moving at its top speed.
how A primary oocyte gives rise to
ATP synthesis in chloroplasts is very similar to that in mitochondria: Electron transport is coupled to the formation of a proton (H+) gradient across a membrane.
Biotechnology permits the use of living organisms or their processes for human needs or purposes. Currently, this topic includes such general examples as cloning,
Suppose when increasing magnification from high dry to oil immersion, should the iris diaphragm be open or closed? How is this done?
Assume you performed a gram stain on a sample from a pure culture of bacteria and observed a field of red and purple cocci. Adjacent cell were not always the similar colour. What do you conclude.
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