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In a typical human cell, replication of the entire genome takes about a day.
(a) A complex of mammalian DNA polymerase and the other enzymes necessary for replication can copy ~ 50 bases per second. Is there a contradiction? Explain!
(b) A typical tumor doubles in size only every 100 days (although this varies significantly depending on the type of tumor). Can you speculate on why this is so much slower than the rate at which the genome can replicate?
Briefly compare similarties in the release of the contents of cortical granules during the fertilization of the sea urchin ovum, with the release of neurotransmitters from terminal knobs of a stimulated neuron.
Discuss and explain how you would calculate delta G for the reaction: glucose+6O2---> 6CO2+6H2O. If you were told that this reaction is highly exergonic.
Create the process of initiation of translation, keeping in mind the molecules needed for translation. What regulates the proper positioning of the ribosome during initiation of translation?
A miRNA regulates its target mRNA through degradation. Let us suppose miRNA-199 targets Blimp1. Which progenitor population in the developing embryo will be affected?
A black A/A B? B C? C is crossed with a colourless a/a b/b c/c to give a black F1. The F1 is selfed. What proportion of the F2 individuals is colourless.
Determine what is the currently accepted scientific explanation for anthropogenic global climate change?
Explain the differences in population growth patterns of the two paramecium species. What does this tell you about how Paramecium aurelia uses available resources.
Three bases per codon are the minimum necessary to code for twenty different amino acids when four different bases are involved.
Assume you isolate the enzyme that synthesizes folic acid in bacteria and conduct few enzyme kinetics experiments. You discover, not surprisingly, that sulfa drugs inhibit enzyme's activity
Write an equation for ethyl acetate from ehyl alcohol, acetic acid, and concentrated sulfuric acid to illustrate the formation of the ester.
Why a defendant's genes do not excuse criminal behaivor.
You now grow Daphnia and Bosmina together. Suppose they remain limited by phytoplankton. What genetic basis of erminette pattern is suggested? How would you test your hypothesis.
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