Find the maximum possible percent paralysis

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Anesthesia induces muscle relaxation (paralysis) and unconsciousness in the patient. Muscle relaxation can be monitored using electromyogram signals from nerves in the hand; unconsciousness can be monitored using the cardiovascular system's mean arterial pressure. The anesthetic drug is a mixture of isoflurane and atracurium. An approximate model relating muscle relaxation to the percent isoflurane in the mixture is

1083_formula.jpg

where P(s) is muscle relaxation measured as a fraction of total paralysis (normalized to unity) and U(s) is the percent mixture of isoflurane (Link- ens, 1992). [Section: 4.6]

a. Find the damping ratio and the natural frequency of the paralysis transient response.

b. Find the maximum possible percent paralysis if a 2% mixture of isoflurane is used.

c. Plot the step response of paralysis if a 1% mixture of isoflurane is used.

d. What percent isoflurane would have to be used for 100% paralysis?

Reference no: EM131199584

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