Explain why mutations in rb can lead to tumors

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1. Muscle contraction is a multistep process that starts with firing of an action potential. Describe the steps involved in this process. A complete answer must include, at minimum, the structures and steps involved in firing an action potential, the production and release of neurotransmitter, and the structure and function of the contractile apparatus.

2. The mitogen, EGFIV, is a paracrine signal that causes inactivation of Retinoblastoma (Rb), through a signaling pathway that includes a receptor tyrosine kinas and Ras. Describe every single step that occurs from EGFIV binding to the receptor to turning on transcription of cell proliferation genes. Explain why mutations in Rb can lead to tumors.

Reference no: EM133335400

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