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Problem
10 years have passed and unfortunately Emily has suffered 2 more acute myocardial infarctions, with the most recent one requiring a triple coronary artery graft surgery. Due to repeated infarctions, a significant number of her cardiomyocytes have died, and her heart is pumping with less efficiency. She presents to her GP complaining of shortness of breath and swelling around her ankles. Her GP decides to request an echocardiogram to check her heart function. Her end-diastolic volume (EDV) is 150ml and her end-systolic volume (ESV) is 95ml.
Question I. As Emily's condition progresses, she starts to accumulate fluid. Describe the RAAS system and how it works to maintain blood pressure and use this description to explain why Emily is accumulating fluid.
Question II. Explain why Emily is experiencing the symptoms described.
Question III. Emily is suffering from ischemic cardiomyopathy. Give examples of 3 other types/causes of cardiomyopathy and describe their respective disease processes.
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