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Question: Show the activity is to help you practice identifying the types of DNA mutations (point mutation, insertion, and deletion) discussed in class and what affect they can have on the resulting protein transcribed and translated from them.
You are given a "Normal Gene" below and three "Mutated Gene." The mutations in DNA and mRNA are shown bolded in blue.
What you need to do:
1.) For both the normal and mutated gene sequences, you will have to use your codon dictionary to finish translating the amino acids from the provided mRNA codons. You are provided the first methionine (MET), but will need to finish the translation. Make sure to show the peptide bonds by using "-" and write a stop codon as (Stop) to indicate that you know it is not an amino acid. If a stop is removed, then just write "..." after the last amino acid to indicate the sequence could continue.
2.) Then you will need to examine the provided DNA mutations to determine what type of mutation is represented in the "Mutated Gene."
3.) Explain what effect each mutation had on the amino acid chain (peptide) compare to the original "Normal Gene."
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