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One limitation of SPME methods is the limited adsorption capacity of the fiber due to the short length (~1 cm) and diameter (~100 um) typically exposed to Analytes. Explain for the analysis of drinking water samples for chloroform, the SPME fiber is normally immersed into a 3.0mL volume of water for 30 minutes as well as then injected directly into a GC. Detection utilizing an electron capture detector provides an absolute limit of detection of 0.5 pg for chloroform. The maximum mass of chloroform that can be adsorbed by the fiber after a 30 minute exposure is 350 ng. The extraction efficiency for chloroform utilizing the SPME method is 85% throughout the entire concentration range that can be determined. The million dollar question- Explain what concentration range (in ug/L) can be determined using this technique?
Show all the steps in the mechanism for the following reaction, When benzene is mixed with deuterated sulfuric acid, deuterium is slowly incorporated onto the ring. Show the mechanism for this reaction and explain how this relates the sulfonation of ..
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