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A brilliant scientist has discovered a new anti-inflammatory agent, Xious, that is capable of preventing the onset of, and therapeutically down-regulating the inflammatory response in several animal models of inflammatory autoimmunity. Prior to human trials it is critical to determine if Xious compromises treated individuals in their ability to respond to microbial infections. To test this, the murine model of cutaneous infection with Staphylococcus aureus was utilized.
In this model, mice are inoculated subcutaneously with synthetic beads coated with S. aureus. The development, and then healing, of skin abscesses is the mechanism utilized to test the immunological response. Mice received either therapeutic doses of Xious or a placebo prior to infection. Mice treated with Xious developed significantly smaller abscesses compared to placebo treated mice. Explain the two conclusions that may be drawn from this outcome. Identify what information you would need to know to distinguish between these two conclusions.
The amino acid sequence of this polypeptide was determined in series of mutants listed in parts a. through e. For each mutant, indicate the type of change that occurred in the DNA (single-base substitution, insertion, deletion) and the phenotypic ..
Compare functional magnetic resonance imaging and magnetoencephalography with regard to spatial and temporal resolution.
What is the prognosis on genetic diseases in the future? Do you believe that microsurgery to "fix" chromosomal aberrations will someday prevent the diseases that are listed in the List of Genetically Mediated Diseases in Humans
Select one of the topics listed below: 1. Genetically modified organisms (GMOs). 2. Stem cells. 3. Fracking (hydraulic fracturing) and tar sands (oil sands)
Which of the following exerts the most important effect to activate proenzymes?
What changes in the genome would we expect if the size of a organism physically changes? What would be the resulting observation in the world around us if this size change were a genetic alteration?
q. some prey form groups aggregate in the presence of a predator. one benefit of aggregation may result from defensive
A true breeding wild-type strain of flies was crossed to another strain homozygous for the recessive X-linked mutant alleles m, r, and v. The F1 female offspring were testcrossed to a recessive strain of males. The following offspring were examine..
You are currently working as a pathologist (study of infectious disease) and you are given a bacterial sample that needs to be identified. How would you test this bacterium with live organisms
Regarding control of gene expression in eukaryotes, what effect does the binding of transcription factors to upstream promoter elements.
Explain what your personal motivation/inspiration/reasons are for wanting to live a healthy and active lifestyle. What do you have to face to reach your goal
a give two distinguishing characteristics of a trna molecule.b in translation what does the ribosome do?c with
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