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Assignment:
1. A 32-year-old woman presents with complaints of drooping eyelids, difficulty chewing and swallowing and weakness of her arms and legs that is less severe in the morning. She reports difficulty climbing stairs and lifting objects. Her clinical exam confirms weakness of her eyelids and jaw muscles. She is told she may have myasthenia gravis and is scheduled for a blood test to assess for antibodies.
a. Explain the pathogenesis of this woman's symptoms as the relate to myasthenia gravis.
b. Explain how the blood test for antibodies can be used to assist in the diagnosis.
c. Explain the rationale for avoiding aminoglycoside antibiotics for treatment of infections in this woman.
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