Solution-Explain the origins of the diastereoselectivity

Explain the origins of the diastereoselectivity observed

Assignment Help Chemistry

Reference no: EM13894356

Question 1:

The alkylation of "Evans" enolates is very highly diastereoselective as we have discussed, and shown below.

2234_Alkylation of Evans.jpg

Part 1. Show how Compound 1 is prepared from common starting materials.

Part 2. Explain the origins of the diastereoselectivity observed in Compound 2

Part 3. Show how Compound 2 is efficiently converted into Compound 3

Question 2:

Upon treatment with the strong base sodium hexamethyldisilazide (NaHMDS), one of the compounds shown undergoes intramolecular cyclization to give a tricyclic ketone.

The other compound does not cyclize. Indicate which compound will cyclize and provide an explanation for your selection.

564_Alkylation of Evans1.jpg

Reference no: EM13894356

Questions Cloud

What the short-run average cost : In the short run, capital is a fixed cost. Draw, for a few different values of K, what the short-run average cost, SRAC, looks like in relation to the long-run average cost.

Both bond-percentage change in price : Both Bond Sam and Bond Dave have 10 percent coupons, make semiannual payments, and are priced at par value. Bond Sam has three years to maturity, whereas Bond Dave has 18 years to maturity. Percentage change in price of Bond Dave?

Designing a database for an antique store : Consider designing a database for an antique store. What entities would you include? What would their attributes be?

What do you expect your professional life would be like : What do you expect your professional life would be like for the two different jobs? Which job do you think is more secure?

Explain the origins of the diastereoselectivity observed : Show how Compound 1 is prepared from common starting materials and explain the origins of the diastereoselectivity observed in Compound 2

The bonds make semiannual payments : Stone Sour Corp. issued 20-year bonds 8 years ago at a coupon rate of 8.70 percent. The bonds make semiannual payments. If these bonds currently sell for 108 percent of par value, what is the YTM?

Cost of Equity and CAPM : Booher Book Stores has a beta of 0.6. The yield on a 3-month T-bill is 3% and the yield on a 10-year T-bond is 6.5%. The market risk premium is 4%. What is the estimated cost of common equity using the CAPM?

Gaap and ifrs address accounting processes from different : GAAP and IFRS address accounting processes from different perspectives

Difference between perpetual and periodic inventory : Describe the difference between perpetual and periodic inventory

User Account

All Pages

Explain the origins of the diastereoselectivity observed

Reference no: EM13894356

Reference no: EM13894356

Questions Cloud

Reviews

Write a Review

Chemistry Questions & Answers

Steps in the mechanism for the following reaction

Prior to placing piece of metal into the graduated cylinder

Write the structures of the saytzeff elimination

Calculate ph - chemistry questions

How many mols of hydrogen can produce

Analysis of corrosion mechanisms

Chemical and pharmaceutical science

Calculate the approximate sulphur

What is the structure - stereochemistry

Design a qualitative analysis scheme

What will be the resultant pressure

The 1h nmr spectrum

Assured A++ Grade

Academics

Major Subjects

Majors

Get In Touch

TERMS & POLICIES

HELP & SUPPORT