Explain the non-enzymatic hydrolysis of urea

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Reference no: EM13528516

Urease catalysis the hydrolysis of urea to ammonia and carbon dioxide. The nonenzymatic hydrolysis at 21'C has an activation energy barrier of 30kcal/mol, whereas that for the enzymatic reaction is 11 kcal/mol.

(a) Calculate how much enzyme accelerates the reaction over the non-catalyzed reaction?

(b) Calculate the temperature that will be required for the non-enzymatic hydrolysis of urea to proceed as rapidly as the enzymatic hydrolysis at 21'C

Reference no: EM13528516

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