Explain the etiopathogenesis of the disease

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Question: A 65-year-old man, a chronic smoker, diagnosed to have chronic obstructive pulmonary disease presented with a history of upper abdominal discomfort, loss of appetite, significant lethargy, and progressive weight loss of 1 year duration. He also had a cough with scant mucoid expectoration and progressive exertional breathlessness for a duration of 2 years.

The patient also reported two episodes of gum bleeding over the last 2 months, which resolved spontaneously. There was no history of any other bleeding manifestation, swellings, or night sweats. On examination, the patient's blood pressure was 140/90 mm Hg and his pulse rate was regular, at 88/min. He was afebrile with respiratory rate of 20/min. General examination revealed normal oral hygiene, mild pallor, and mild pedal oedema. Abdominal examination revealed moderate hepatosplenomegaly and respiratory system showed bilateral diffuse rhonchi.

Instructions

1. Recognize and describe the essential pathology in the virtual slide and take snapshots of what you are describing
2. Classify the lesion and explain the basis based solely on the pathologic features
a. Reactive/inflammatory
b. Neoplastic
3. If neoplastic, state the probable classification based solely on the pathologic features
a. Acute leukemia
b. Chronic leukemia
4. Explain the etiopathogenesis of the disease including the molecular aspects

5. What is your diagnosis

Reference no: EM133360848

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