Explain the direct effects of bromination of vanillin

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Reference no: EM13511693

What is the direct effects of bromination of vanillin? Debating between 5-bromovanillin and 6-bromovanillin. One would expect 5-bromovanillin in the meta position based on stability of all substituents, but 6-bromovanillin in the ortho position avoids more steric hindrance from the alcohol and the -OR group.

Reference no: EM13511693

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