Explain optimize the half-life of elimination of the drug

Reference no: EM13213313

For drug development, it is crucial to optimize the half-life of elimination of the drug so that the drug has long enough to act but not enough time to cause harmful side-effect. After the intravenous administration of a new beta blocker, the blood plasma of a patient was analysed for the remaining drug and the data is shown below, where c is the drug concentration measured at a time t after the injection.

Time (min) 30 60 120 150 240 360 480
c (ng cm-3) 699 622 413 292 152 60 24
i. Determine graphically whether the removal of the drug is a first order or second order rate process.
ii. Calculate the rate constant for the process.
iii. Determine the half life of the process.

Reference no: EM13213313

Questions Cloud

Find out the characteristics of the unknown acid : Determine the following characteristics of the unknown acid: molecular formula, molar mass, Lewis structure.

Depict the lewis dot structure of phosgene : Draw the Lewis dot structure of phosgene. Include all 3 resonance forms by alternating the double bond among the 3 terminal atoms. Which resonance structure is best?

Explain the hydrogen atom relaxes to a lower energy level : the hydrogen atom relaxes to a lower energy level, emitting light of 397 nm. What is the value of n for the level to which the electron relaxed.

Compute the equilibrium temperature : The specific heat of Al and water are 0.90 J/(goC) and 4.184 J/(goC), respectively. Calculate the equilibrium temperature.

Explain optimize the half-life of elimination of the drug : For drug development, it is crucial to optimize the half-life of elimination of the drug so that the drug has long enough to act but not enough time to cause harmful side-effect.

Explain the vapor pressure of pure ethanol : What mass of C2H5OH should be added to 535 kg of the paraffin in formulating the mixture if the vapor pressure of ethanol at 35°C over the mixture is to be 8 torr? The vapor pressure of pure ethanol at 35°C is 100 torr.

State an expression for the quantity : Write an expression for the quantity 506000 cm in which it is clear that all the zeros are significant.

Evaluate the coefficients of a linear regression equation : Evaluate the coefficients of a linear regression equation and evaluate the coefficient of correlation for the linear regression model.

A colorless liquid that is commonly known as grain alcohol : a colorless liquid that is commonly known as grain alcohol, is 0.789 g/mL. Calculate the mass of 17.4 mL of the liquid.

User Account

All Pages