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Question: At the start of mitosis, sister chromatids are held together by a complex of proteins. Separase is an enzymes that cleaves the complex, enabling the choromatids to separate during mitosis. Separase is overexpressed in many cancer cells, and scientists hypothesized that they might be able to slow or stop the growth of cancer cells by blocking the activity of separase. The scientists found a compound they named Sepin-1 that appears to effectively cleave and thus inactivate purified separase protein in vitro (in a test tube).
In normal cells, separase is kept in an inactive state until it is needed. Explain how the progression of cells past sequential cell cycle checkpoints and the activity of enzymes such as separase is controlled by interactions between two major groups of regulatory proteins.
A transcriptional unit of rRNA with strands of nascent rRNA getting progressively larger as they get closer to the end of the unit, a structure that looks much like an arrowhead. What is the significance of the space between the two arrowheads? Pl..
Meyer and Overton, at the turn of the last century, conducted a seminal study on the influence/efficacy of anesthetics on cell membrane fluidity. Briefly explain their findings in the context of biochemistry.
What is being done in captivity to conserve? What is being done in the wild to conserve
write the genotypic designation for THREE DIFFERENT mutations in two genes coding for enzymes in proline biosynthesis. One mutation leads to the loss of the first dedicated enzyme in proline biosynthesis.
How are the attributes of the concept of health promotion evident in this case presentation?
I have 30µg of a primer, whose molecular weight is 600. Determine how much water should I add to get a stock primer concentration of 100µM?
What is the relationship between an antigen, an antibody, and the plasma membrane?
How is that a trained athlete could die of dehydration? Please use physiology explanations in your response
Compare the impact of a mutation in the DNA sequence of a gene with the impact of a mutation in the intron region of DNA.
What are the differences in the impact on the environment between anthropogenic (those caused by humans) and natural changes to an environment?
What are the major differences between a primary and a secondary lymphatic organ? Give two examples of each. Define acquired immunity and give two examples
You study two populations of zebra skipper butterflies, one on the mainland and the other on a large island several hundred miles off the coast of Brazil. In the mainland population, males and females are nearly identical in size. By contrast, fem..
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