Explain how dnp can be used to reduce weight

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Dinitrophenol (DNP) was used in the manufacture of munitions in World War I. In the 1930s, it was used as a weight loss drug. Use in the U.S. cannot be regulated by the FDA because DNP is considered a dietary supplement. Attempts to ban the drug in the U.K. following the death of four users in 2015 failed in Parliament. DNP is a small molecule that is soluble in the mitochondrial inner membrane. The hydroxyl group reversibly dissociates a proton.

A. Predict the effect of DNP on the electrochemical gradient across the inner mitochondrial membrane.

B. Explain how DNP can be used to reduce weight.

Reference no: EM132724051

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