Explain anionic imide nucleophile

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One approach to the synthesis of virstatin is shown above. An SN2 reaction of an anionic imide nucleophile (formed by deprotonation of1) with an alkyl halide electrophile 2 affords virstatin ethyl ester 3 Base-inducedhydrolysis followed by acidification yields virstati 4

Q1. What would be an alternative way to make this compound?

Reference no: EM13186377

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Explain anionic imide nucleophile : One approach to the synthesis of virstatin is shown above. An SN2 reaction of an anionic imide nucleophile (formed by deprotonation of1) with an alkyl halide electrophile 2 affords virstatin ethyl ester 3 Base-inducedhydrolysis

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