Explain amitriptyline and nortriptyline over the toxic dose

Reference no: EM13225990

Eighteen blood and 14 tissue and fluid samples were taken at autopsy 16 h after the death of a 34- year-old female.Amitripyline was found in her room.Ranges of drug concentrations in blood were amitriptyline1.8 to 20.2 micrograms/mL,nortriptyline 0.6 to 7.3 micrograms/mL,levels were lowest in femoral vein and highest in pulmonary vein blood. why was nortripyline measured here? was there post-mortem redistribution? Explain.Were amitriptyline and nortriptyline over the toxic dose? Acute overdose/rapid death or chronic administration/show death? Explain

Reference no: EM13225990

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