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Case Study: JM is a 45-year-old female admitted with alcohol intoxication. Would like to detox. She reports a 25-year history of alcohol dependence with multiple relapses. Reports history of withdrawal seizures. Current Clinical Institute Withdrawal Assessment Alcohol Scale Revised (CIWA-AR) is 18. She denies any past medical history. She denies taking any medications or other substance use. Her Labs are all normal except elevated LFTs.
QUESTIONS:
1. DISCUSS/EXPAIN in detail the pharmacological treatment to maintain abstinence from alcohol.
2. DISCUSS/EXPAIN in detail the MOA and potential adverse reactions.
3. DISCUSS/EXPAIN in detail the factors, such as nonadherence, cost, reimbursement, health insurance.
4. DISCUSS/EXPAIN in detail a pharmacological treatment for a patient who has history of adherence problems with disulfiram, has insurance that does not require prescription copayment.
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