Reference no: EM133276415
Assignment:
Respond to the discussion below. Responses should be thorough and thoughtful. Just posting an "I agree" or "Good ideas" will not be considered adequate. Support statements with examples, experiences, or references.
Discussion:
In a person who suffers from obesity, the mobilization of fatty acids becomes excessive and can cause insulin sensitivity to be impaired (Schenk et al., 2009). In a study conducted to examine insulin sensitivity, a person who has lost a large amount of weight showed an increase in insulin sensitivity. This improvement showed that there was at least a 60% increase in insulin sensitivity (Schenk et al., 2009). In the event that fatty acid mobilization is decreased, insulin sensitivity will increase since the molecules that impair it will be reduced. Along with this, it was also indicated that increased sensitivity "may in part be due to a reduction in the pro-inflammatory/stress response in skeletal muscle" (Schenk et al., 2009).
Reference
Schenk, S., Harber, M. P., Shrivastava, C. R., Burant, C. F., & Horowitz, J. F. (2009, October 15). Improved Insulin Sensitivity After Weight Loss and Exercise Training is Mediated by a Reduction in Plasma Fatty Acid Mobilization, Not Enhanced Oxidative Capacity. The Journal of physiology.