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Question
A 14-year-old boy with no significant past medical history is brought to the clinic by his mother for evaluation of sensitivity and discomfort to his breast region bilaterally for a month. He has been staying in the house without a shirt on because his nipples are particularly sensitive when rubbed against clothing. Vital signs are normal. His body mass index BMI is 19 kg/m2, and he appears well-developed and lean. The physical examination of both breasts displays a tender, rubbery ridge of mobile glandular tissue 2 cm in diameter symmetrically distributed under the nipple. There are no other nipple changes or discharge. There is no lymphadenopathy or abdominal mass. Genital and testicular examination is normal at Tanner stage 4 with normal testicular volume and no mass. The remainder of the physical examination is within normal limits with no signs of thyroid, liver, or kidney disease. He denies any medication, steroids, alcohol, or drug use. What is the most likely diagnosis? Pubertal gynecomastia Klinefelter syndrome Pseudogynecomastia Cryptorchidism.
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