Evaluating expression of twist and snail

Assignment Help Biology
Reference no: EM132548029

Your colleague is perplexed - he tells you that he's monitoring the EMT in the mice by evaluating expression of Twist and Snail (known to be required for the EMT), which do increase as he observes the tumor cells breaking through the basement membrane of the colon epithelium. He's looking at their expression via immunoblots. But he's confused because b-catenin levels stay about the same and he expected them to increase. You reassure him that this observation is consistent with the EMT. What is your explanation and what simple experiment can you suggest that would demonstrate your explanation?

Reference no: EM132548029

Questions Cloud

Viewing the interior of the pancreas : Would a capsule endoscope be useful for viewing the interior of the pancreas? Explain.
Determining the environmental variation : Hydrangea plant species, based on environmental variation, possess some sort of phenotypic differentiation in color pattering
Find a specific example of research being : Find a specific example of research being done on beneficial microbes
Example of how you would assay for overexpression : Give one example of how you would assay for overexpression of RTK
Evaluating expression of twist and snail : Your colleague is perplexed - he tells you that he's monitoring the EMT in the mice by evaluating expression of Twist and
Therapeutic approach for solid tumors : In CAR-T therapy, T cells are engineered so that they have high selectivity for tumor cells. From the list below, indicate
Discuss the effects of blood glucose level : Discuss the effects of blood glucose level and what you observed in about the levels in the lab. What did you learn about blood glucose
Identify a project concept that could be executed : Identify a project concept that could be executed at either your workplace or home (such as a planned extension, overhaul or refurbishment
Person regarding mendel experiment : Impact of content on yourself or a person regarding mendel's experiment.

Reviews

Write a Review

Biology Questions & Answers

  What flaws if any can you find in the given experiment

Suppose a scientist observes an abnormality in the growth of robin embryos in a certain area. What flaws, if any, can you find in this experiment that might lead you to question the scientist's conclusions?

  How remove essentially all of the salt from the solution

Suppose you have a solution containing both salt (NaCl) and glucose, and dialysis tubing with a pore size that allows the passage of Na+ and Cl- ions, but doesn't allow the passage of glucose. How could you remove essentially all of the salt from ..

  Define protein conformation change

Some might argue that the conformational change of proteins is the single most important concept in biochemistry.

  Explain the dose-response relationship

Explain the dose-response relationship between exercise and risk of death from coronary heart disease.

  Which of the following includes highest levels of hierarchy

Which of the following includes Highest levels of hierarchy?

  Pattern of relatedness among four individuals

Determine what pattern of relatedness would you infer among four individuals based only on the following sequences from the same place in their chromosomes?

  About the evolution of metabolism

A taxon of living bacteria uses the same electron transportchain for both aerobic respiration and photosynthesis. It is thought that this is an ancestral trait in prokaryotes. What does this suggest about the evolution of metabolism?

  Explain transcription and translation in detail

1)Explain transcription and translation in detail 2)Explain DNA replication

  Summarize the effects histamines can have on the body

Summarize the effects histamines can have on the body. What is the purpose of an antihistamine?

  What is the geologic timescale

What is the geologic timescale? How is it organized? List some major events and dates in this timescale.

  Information storage in the primitive cell

Could RNA have been the original site of information storage in the primitive cell? A difficult problem with this possibility is that

  In what stage of cell division does the dna replicate

In what stage of cell division does the DNA replicate?

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd