Evaluate the ratio of ionized to unionized drug forms

Assignment Help Chemistry
Reference no: EM13546264

The OTC antihistamine chlorpheniramine maleate is a cationic acid with an unionized conjugate base and a pKa of 9.4. Calculate the ratio of ionized to unionized drug forms that would exist in the plasma at physiological pH (7.4). What is the percent ionized to unionized?

Reference no: EM13546264

Questions Cloud

What is the mass of water in the pool : A 9.00 x 15.0 swimming pool slopes linearly from a 1.00 depth at one end to a 3.80 depth at the other. What is the mass of water in the pool
What magnitude impulse is delivered to the player : A baseball player of mass 73.5 kg running at 7.36 m/s slides into home plate. What magnitude impulse is delivered to the player by friction
Explain what is the percent ionized to unionized : The antibacterial agent sulfamethoxazole is an unionized acid with a pKa of 5.0. What is the ratio of this drug in buffered gastric fluid of pH 3.0. What is the percent ionized to unionized
Evaluate the impulse was given to the ball by the floor : A ball of mass 0.120 kg is dropped from rest from a height of 1.25 m. What impulse was given to the ball by the floor
Evaluate the ratio of ionized to unionized drug forms : Calculate the ratio of ionized to unionized drug forms that would exist in the plasma at physiological pH (7.4). What is the percent ionized to unionized
Compute the amount of cash received : Compute the amount of cash received from the sale of the property, plant, and equipment - During the year, property, plant, and equipment with an original cost of $35,000 was sold for a gain of $4,500.
Find the new angular velocity of the two astronauts : Two astronauts of equal mass 76 kg are holding on to opposite ends of a straight rope in space. The length of the rope between them is 18 meters. What is the new angular velocity of the two astronauts
Explain solar energy collectors to power the planet : How much of Earth's surface would we need to cover with solar energy collectors to power the planet for use by all humans. Assume that the solar energy collectors can only convert 10 of the available sunlight into useful power.
Calculate the velocity of a transverse wave on a rope : Calculate the velocity of a transverse wave on a rope when the tension in the rope os 10 newtons, its length is 0.8 meters, and its mass is 0.05 kg

Reviews

Write a Review

Chemistry Questions & Answers

  Explain what will the final temperature of the hg be

Between 0 degrees Celsius and and 30 degrees Celsius, mercury has a specific heat of 0.138 J/g*C. If 200 J of heat are removed from 100 g of Hg at 20 degrees Celsius, what will the final temperature of the Hg be

  How to calculate the number of moles of no2(g)

At this temperature, calculate the number of moles of NO2(g) that must be added to 2.76 mol of SO2(g) in order to form 1.20 mol of SO3(g) at equilibrium.

  Explain what is the partial pressure of nh3

A mixture of gases contains 10.20g of N2 , 1.80g of H2, and 8.15 of NH3 . The total pressure of the mixture is 1.90atm. What is the partial pressure of N2? What is the partial pressure of H2. What is the partial pressure of NH3.

  Define the molar concentration of hydrochloric acid solution

A standard solution of sodium hydroxide has a molar concentration of 0.128M. You use 25.00ml of a solution of hydrochloric acid and this requires 32.75ml of the standardized sodium hydroxide solution to reach the endpoint. WHAT IS THE molar concen..

  Depict an absorption spectrum of leucoindigo

Draw an absorption spectrum of leucoindigo. What color is absorbed by leucoindigo? Draw a simple energy level diagram of leucoindigo. Calculate the energy difference between energy levels.

  How to calculate the molarity of the solution

A 3.18 L sample of hydrogen chloride (HCl) gas at 1.64 atm and 31 degrees C is completely disolved in 710 mL of water to form hydrochloric acid solution. Calculate the molarity of the solution. Assume no change in volume

  Describe what are the molecular and mass densities

Consider H2, D2, and H20, treated as ideal gases at pressures of 1 atm and temperatures of 293.2 K.

  Explain natural water was determined by precipitation

The iron (55.847 g/mol) in a 700.0 mL sample of a natural water was determined by precipitation of the cation as hydrated Fe2O3. The precipitate was filtered

  Calculate the mass of silver nitrate

Calculate the mass of silver nitrate (in grams) in a 145 mL solution of 5.38 M AgNO3.

  Explain ammonia chemically reacts with oxygen gas

Ammonia(NH3) chemically reacts with oxygen gas (O2) to produce nitric oxide (NO)and water. What mass of ammonia is consumed by the reaction of 1.50g of oxygen gas

  Compute mass of water removed from the pulp

A mist is observed to form on the mirror at a temperature 40C. Calculate mass of water removed from the pulp (kg/min) and the volumetric flow rate of air entering the system.

  Electrophilic atom and what is the most nucleophilic atom

Considering the likely HOMO and LUMO of L-serine methyl ester, what would be the most electrophilic atom and what would be the most nucleophilic atom

Free Assignment Quote

Assured A++ Grade

Get guaranteed satisfaction & time on delivery in every assignment order you paid with us! We ensure premium quality solution document along with free turntin report!

All rights reserved! Copyrights ©2019-2020 ExpertsMind IT Educational Pvt Ltd