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Guaifenesin (Guaiacol glyceryl ether, 3-(2-Methoxyphenoxy)-1,2-propanediol, C10H14O4) is an expectorant that is found in cough medicines such as ActifedTM and RobitussinTM. U.S. 4,390,732 (to Degussa) describes a preparation of the active pharmaceutical ingredient (API) from guaiacol (2-methoxyphenol, C7H8O2) and glycidol (3-hydroxy propylene oxide, C3H6O2). When the reaction is catalyzed by NaOH, the reaction yield is 93.8%. The product is purified in a thin-film evaporator giving an overall plant yield of 87%.
a. Estimate the feed flow rates of glycine and guaiacol that would be needed to produce 100 kg/day of the API.
b. Estimate how much product is lost in the thin-film evaporator.
c. How would you recover the product lost in the evaporator?
How will the mole fractions of benzene and toluene in the liquid change with time (increase, decrease, or remain constant)? Explain your answer.
The horsepower output from the prime mover to drive the generator at this load.
What is the temperature of the exit stream? Should you take this idea to your superiors for further discussions?
At one time, biologists thought that fungi were merely forms of plants that had lost their chlorophyll and had returned to saprotrophy to gain food. Why is this no longer considered a solid theory?
-12 the gravimetric composition and properties of two different typical fuels i.e. coal and fuel oil is tabulated below- Parameters coal fuel oil Composition weight% -- C 76 85 H 4.5 11.5 S 0.5 3.5 N 1.0 -- O 3.0
Application of reverse osmosis principles for the desalination of sea water
An LiClIfiO solution at 298.15 K (25°C) is made by adiabatically mixing cool water at 283.15 K (10°C) with a 20-mol-% LiC1/H20 solution at 298.15 K (25°C). What is the composition of the solution formed?
What is the molar concentration of the ammonia in the liquid at the interface?
A 95 turn square wire coil of area 0.040 m2 rotates about a vertical axis at 1730 rpm, as indicated in Figure P20.30. The horizontal component of the Earth's magnetic field at the location of the loop is 2.0 10-5 T.
Assuming 8.0 hours of useful sunlight per day, calculate the minimum solar panel surface area necessary to provide all of a typical home's electricity. (See Exercise 96 for the energy rate supplied by the sun.)
If the speed is reduced to 1150 r/min, estimate the rate of water delivery and the developed head in feet if the pump operation is ideal.
1000 kg/hr of a mixture containing 42 mole percent heptane and 58 mole percent ethyl benzene is to be fractionated to a distillate containing 97 mole percent heptane and a residue containing 99 mole percent ethyl benzene using a total condenser an..
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