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Enalaprilat is a competitive inhibitor of the angiotensin-converting enzyme (ACE), which cleaves the blood-pressure regulating peptide angiotensin I. ACE has a KM = 52 μM for angiotensin I, which is present in plasma at a concentration of 75 μM. When enalaprilat is present at 2.4 nM, the activity of ACE in plasma is 10% of its uninhibited activity. What is the value of KI for enalaprilat?
The left atrium is damaged and is generating a great resistance to blood coming from pulmonary vein. What happens due to this pressure? A: back up of blood causing a subsequent back flow of blood into the inferior vena cava
What would the cardia output be of a patient with a blood pressure of 120/75, a pulse rate of 40 beats/minute, a stroke volume of 70mL/beat, and a respiratory rate of 25 breaths a minute?
The SalI restriction site in box is polymorphic. Geese with a functional alchemase gene secrete gold into egg white when they are fed a diet rich in lead.
You sample a population of Salmonella typhimurium from a popular local hamburger joint Howdyburger. You find 9 isolates (clones) that are resistant to the antibiotics ampicillin and kanamycin, 32 isolates that are resistant to amipicillin but susc..
Assume you are purifying a protein on a weak cation exchanger and it comes off at 300mM salt. predict what salt concentraiton the protein would come off if you used a strong cation exchanger.
The drug vincristine is used to treat many cancers. Itapparently works by causing microtubules to depolymerize (breaksapart microtubules). Vincristine use has many side effects,including loss of dividing cells and nerve problem due to transportof neu..
Analyze the transition of medical training, early hospitals, and medical advancements up to the present time. Justify the need for doctors with advanced medical training in the health care industry
Which of the following populations/species would exhibit noage-structure? An example of a small number system is:
What is herd immunity? How does it work? What evidence do we have for it? What measures are currently taken in the U.S. to maintain it for certain diseases? What is a vaccine? How are vaccines made?
Mammals contain a diploid genome consisting of at least 109 bp. Each group of 200 bp of DNA is combined with 9 histones into a nucleosome.
Hemophilia is caused by a recessive sex-linked allele that is carried on the X chromosome. A male hemophiliac has a child with a woman who is a carrier for the condition.
Provided that a substance's permeability represents the distance it can travel in a lipid bilayer per unit time, how long would it take an uncharged.
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