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Question: Vinblastine is a pharmaceutical used to treat several cancers, such as lung and breast cancer and Hodgkin's lymphoma. It binds tubulin, a protein found in microtubules of the cytoskeleton, and prevents the proper formation of the mitotic spindle and the kinetochore. Cancer cell reproduce very rapidly, the drug is used to inhibit cell division in the cancer cells.
Considering this mechanism of action, do you predict that vinblastine would be an effective drug to treat a bacterial infection, since bacteria also reproduce rapidly? Provide a brief rationale for your prediction.
CC DD and cc dd individuals were crossed and hte F1 generation was backcrossed to get cc dd parent. 903 Cc Dd, 897 cc dd, 98 Cc dd. c and d are 10 m.u apart.
Describe the reason behind the difference in the physical properties of methane and methanol. Consider the lifestyle in a monastery, how does chant reflect life in the middle Ages.
While discussing their findings, authors have ignored a main threat to the validity of their estimates of the exposure. Explain and discuss this error.
Describe why 0.9 percent NaCl is an isotoinc solution. In another word, please explian the calculation that shows its osmolality is 300mOsm.
Acetylcholine acts at the G-protein-linked receptor on heart muscle to make the heart beat more slowly by the effect of the G protein on a K+ channel. Which one or more of next would enhance this effect of acetylcholine.
Predict equilibrium potentials E K and E Na at a temperature of 13 o C. Suppose that the Na permeability of the cell membrane is 1/50 that of the K permeability, predict the resting potential, E m , assuming that Cl is in equilibrium.
Digestion of the oligonucleotide, AGUACAA, by pancreatic RNase would yield what products. make a restriction map for this plasmid.
A man drops a baseball off of the top of the Empire State Building. If the action force is the pull of the Earth on the ball, then what is the reaction force. What is the most possible diagnosis of the condition described? Explain.
If a transferrin receptor has a cross-sectional area of 50 Angstroms X 100 angstroms (5x10nm), and how many receptors could be accomodated in a 100nm clathrin-coated vesicle assume that only 50% of surface area can be occupied by proteins.
Mr. X, husband of Mrs. X, has just been diagnosed with benign prostatic hyperplasia (BPH). He has been set down a drug in the same category as prazosin named tamulosin
So far while surgery was performed on his neck, the surgeon might not find the parathyroid glands at all. Where should the surgeon look next to find out the tumorous parathyroid gland.
Give examples of potential environmental impact. Give at least two references in addition to your text in support of your position. Be sure to cite your sources including your text using APA style and respond to at least two of your classmates' posti..
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