Duchenne muscular dystrophy results

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Duchenne muscular dystrophy results from an X-linked recessive mutation that abolishes did gene function. Dystrophin, the produce of did, encodes a protein that links the cytoskeleton to the extracellular matrix. To study did more fully you wish to make a mouse model of Duchenne muscular dystrophy. How would you go about making this model? Please include the general steps involved and a diagram of the vector that you would use.

Reference no: EM132931268

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