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Drug is reduced when gastric acid secretion is reduced

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Basic drugs (e.g., cinnarizine) has higher absorption with food. On the other hand, absorption of basic drug is reduced when gastric acid secretion is reduced. I thought a basic drug will be less ionized and thus more absorbed in basic conditions so if gastric acid secretion is reduced, shouldn't it be more absorbed rather than less absorbed?

Reference no: EM133364673

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