Draw the mechanism of peptide hydrolysis by bromelin

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Reference no: EM13114801

The enzyme Bromelin is a cysteine protease from pineapple that utilizes a similar mechanism to serine proteases except the serine is replaced by a cysteine. Draw the mechanism of peptide hydrolysis by Bromelin. Start with the residues involved in catalysis and the substrate, and draw and label the structures for each of the following: 1) Michaelis complex 2) First tetrahedral transition state 3) acyl-enzyme intermediate (and first leaving group) 4) acyl-enzyme complex with attacking water molecule 5) second tetrahedral transition state 6) enzyme product complex.

Reference no: EM13114801

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