Discussion on lethal allele

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Reference no: EM1393905

  1. Understand an allelic series -How many possible alleles are there for any given gene? Is there only one recessive allele for a gene? Is there only one dominant allele for a gene? Is an allele always recessive or dominant with respect to other alleles of the gene?
  2. What is a lethal allele? Are lethal alleles usually dominant or recessive? Are there any exceptions? (Hint: Huntington disease in humans). How do we maintain stocks with lethal alleles?
  3. How can you tell if an allele is lethal? If one of the parents has a lethal allele, would all the possible genotypes be present in the progeny? What would happen to the phenotypic ratios of the progeny?
  4. What is pleiotropy?
  5. How can you tell if a trait is determined by more than one gene? What ratios of phenotypes in the F2 generation would you expect if a trait is determined by a single gene? 
  6. What is epistasis? How can the genotype at a locus affect the phenotype determined by the genotype at another locus? What are complementary gene action, duplicate gene action, dominant suppression, dominant epistasis, and recessive epistasis?

Reference no: EM1393905

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