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Growth factors and their corresponding receptors are commonly overexpressed and/or dysregulated in many cancers. First discuss the interplay between growth factors, their receptors, signaling cascades and the relationship of these three to cancer. Second pick a cancer, such as hepatocellular cancer, where growth factors and their related signaling cascades play an important role in the etiology and progression of the cancer and discuss two rational targets for cancer therapy. In discussing your therapies make sure you explain how you envision these therapies working, which means you may need to explain certain parts of signaling cascades.
What event is responsible for the pacemaker potential in the SA node? A. slow leakage or movement of Na+ ions into the cells B. activation of voltage-gated K+ channels that allow K+ to enter the cell.
Is this an instance of a positive or negative feedback mechanisms? What is the initial stimulus? What is the result.
Discuss the research conducted by the U.S. Forest Service. Choose three of the following topics on which to focus: Smoking Regulations Signs, Public Awareness of Fire Prevention Importance, Fire Prevention Promotion and Enforcement, Enforcement of Fi..
What is the diploid chromosome number in humans and Where in the body could you find a cell with the diploid number of chromosomes?
To get isolated colonies on a plate, only about 300 cells can be in the inoculum. What will happen if the cell density of the inoculum exceeds this number?
A man makes 0 units of an enzyme due to homozygous recessive genes on chromosome 21. His wife makes 100 units of the enzyme due to a heterozygous pair of genes on chromosome 21. They have a son with trisomy 21 who makes 200 units of the enzyme.
What is the frequency of heterozygotes (Aa) in a population in which the frequency of all dominant phenotypes is 0.25 and the population is in H-W equilibrium?
explain the feedback mechanism that maintain homeostasis and give two specific examples of what happen when homeostatic control systems do not function properly.
Explain what riobzymes and proteins have in common in terms of acid-base catalysis. What are the differences?
Describe the ABO system of red blood cells classification and explain the significance of blood types.
Which of the following is not a feature of epithelium?
List the manifestations associated with adrenal medulla hyperfunction and explain how the alterations to normal physiology related to this disorder can cause them.
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