Reference no: EM133332911

Questions: Consider the following research hypothesis, "High dietary intake of soy milk is associated with lower recurrence of breast cancer in women diagnosed previously with this disease". This hypothesis was examined in a historical prospective cohort study which followed 534 women who had breast cancer in remission. The women in the study were identified from a hospital registry. Diet was assessed with a food frequency questionnaire through an interview, and classified 132 women into a high soy milk group. After 15 years, the recurrence of breast cancer was noted in 26 women in the high soy milk group and 93 women in the low soy milk group.

1. Discuss the level of validity of the independent variable; low, moderate, or high?

2. Discuss the likely representativeness of the study participants; low, moderate, or high?

3. What measure of association should be identified to examine the etiologic relationship between the independent and dependent variable?

4. Calculate and interpret this measure of association.

5. What would be an indication that this relationship is statistically significant?

6. What would be an indication of the precision related to the estimate of the relationship between the independent variable and dependent variable in this study?

7. What level of measurement error is likely to exist in the dependent variable measurement; low, moderate or high? Why?

8. What type of information bias is of greatest concern in this study? Why?

9. What type of selection bias is of greatest concern in this study? Why?

10. What is a confounding variable that may affect this study result? What methods could be utilized to reduce its impact?