Discuss the fundamental of single cell sequencing

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Reference no: EM133334291

Assignment:

1. Discuss the fundamental of single cell sequencing. List a few scenarios that it can be applied.

2. GWAS (genome-wide association studies) now become a very powerful tool to study genotype-phenotype ssociation. Discuss the principles of this a technique. List a few sources of database in order to perform GWAS.

3. List the resource/database that you can use to find the full genome of an organism. Use any genome browser, search for the location of human SOD1, also including promoter regions, summarize the exons numbers, adjacent genes and find its regulation region, as well as SNPs.

4. Nowadays there are many online resources available which can help to achieve study goals. Using the database and online tools we have learned in the class, please answer the following questions.

A) Descript the function of Geoprofile? How you can take advantage of this database?

B) Can you predict protein folding? How to use online source to predict protein folding?

C) Using OMIM, search for genes that are associated with a inheritable disease of your interest.

D) Search for SNPs for hemoglobin gene.

E) Using single cell sequencing database, find out the Syn1 gene profiles in cells from human and mouse.

5. How do you think the future of precision medicine? Which types of you think will be benefited from precision medicine, why?

Reference no: EM133334291

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