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1. The Mystery of Tissue Specificity. As a result of advanced genetic and molecular techniques, many germline mutations (inherited mutations passed down to offspring as opposed to somatic mutations acquired during the adult lifetime) associated with an increased risk of developing cancer have been identified(see the COSMIC database) Choose one germline mutation as your topic focus. Discuss the normal function of the gene as well as the role of the mutated gene in cancer development and/or progression, the type of cancer(s) associated with this mutation (keeping in mind classifications from Ch. 2), and the role of the tumor microenvironment in the development and/or progression of the specific cancer discussed. If specific information is not available on the influence of the microenvironment on this particular tumor type, provide informed speculation based on your reading.
2. Tumor viruses.
Choose a well characterized tumor virus as your topic focus (note: you may choose a virus that infects either humans or animals). Discuss the nature of the virus, the type of cancer(s) associated with this virus (keeping in mind classifications from Ch. 2), the role of the virus in tumor formation and/or progression, and the role of environment/microenvironment in the development of the virus-associated cancer. More specifically, being infected with a tumor causing virus does not guarantee the development of cancer (for example, HPV infection and cervical cancer). What environmental factors influence the risk of developing cancer if infected with this virus? If specific information is not available on the influence of environmental/microenvironmental factors on this particular virus-associated tumor type, provide informed speculation based on your reading.
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Why in the world plants evolved such beautiful colours and shapes and create such wonderful scents. What do you tell her.
If a population with two alleles is at Hardy-Weinberg equilibrium and the frequency of one allele is 0.6, what is the heterozygote frequency.
Critically explain the environment and outcome of the environmental problems, the strategies and factors which affect the environment and prevention of the environmental strategies with the graphical explanation.
What defence was successful in preventing you from grab the snake. While travelling in Texas, you stumble across a snake with red, yellow, and black bands.
What fraction of demes in each set is likely to become fixed for allele A1 versus A2. Explain the differences in head movement available to fish.
If you were asked to create a karyotype from the chromosome spreads you made from HeLa cells in Activity 4.2.1, list materials you would use and explain how you would make the karyotype.
Suppose the Sun had a temperature of 17,400 K (three times its present temperature) but was the same size it is now. How much more energy would the Sun emit per second.
Write down an equation for the complete oxidation of glucose. What does this imply about the volume changes you would view if you simply sealed the pea seeds in a flask.
Which of the follow is NOT a function of meiosis. Generation of genetic diversity by crossing over.
Briefly explain why this mating produces a triploid individual. Why can mitosis proceed normally in triploid cells, but meiosis cannot.
The addition of oligomycin to mitochrondria markedly drecreased both the rate of electron transfer from NADH to oxygen and the rate of ATP formation.define what is the mechanism of inhibition.
Which virus caused it? Why was a viral culture completed after the Gram and acid-fast stain results were obtained.
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