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Assignment:
Summary of "Based on a critical analysis of existing literature, we posit that many of the reported negative health effects of MSG have little relevance for chronic human exposure to low doses. In order for preclinical studies to be significant for human dietary intake, they must mimic the real context of exposure to flavor enhancers (adequate species, dosage, route of administration). Moreover, clinical and epidemiological studies need to have an optimal design, accounting for both added and natural originating MSG, thereby reporting accurate and significant data, that truly impart relevant information on its health effects. Furthermore, we consider that the assessment of MSG impact on nociception and on fetal neurodevelopment, following chronic exposure to dietary doses, represent valid research directions that should be considered."
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