Discuss and feedback adhd treatments target

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Question: discuss and feedback ADHD treatments target the norepinephrine transporter (NET) and this research was looking to measure the differences in NET DNA methylation levels between patients with ADHD and healthy controls. This study only used 23 patients and 23 healthy controls, and a subgroup of 18 patients and 18 healthy controls that participated in positron emission tomography (PET). Results showed differences in NET methylation and hypermethylation in the promoter region of the brain. A defined segment of the NET promoter ("region 1") hypermethylated in patients in comparison with controls. This change ultimately altered NET distribution in several parts of the brain and points to epigenetic dysregulation in ADHD.

Reference no: EM133550241

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