Differentiation of the macrophage into an nk cell

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A major antigen in Mycobacterium tuberculosisa. TLR4b. TLR2c. TLR3d. TLR7 is the thick glycolipid cell wall composed of lipoarabinomannan. Which TLR receptor on the macrophage will be of primary importance in recognizing the bacterial lipoarabinomannan as a PAMP and, therefore, as danger?

Innate immune cells express pathogen recognition receptors (PRR) which bind pathogen-associated molecular patterns (PAMPs) produced by the infectious organism. Which of the following statements best describes the significance of the PRR-PAMP interaction?

a. Activation of innate immune cells to eliminate the infecting pathogen

b. Differentiation of the macrophage into an NK cell

c. Affinity maturation of immunoglobulin molecules

d. Formation of memory macrophage responses

Reference no: EM132800267

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