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Differentiate free vs. bound form of drugs

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Questions

1. The stomach pH is 1.0 and pH of small intestine is 7.0. What is the mechanism for sudden increase of pH? What organ is responsible for this pH change?

2. Describe Class I , II, III, and I drugs.

3. Describe the effect of surface area, concentration gradient and thickness of membrane on rate of absorption.

4. What is the major site of oral drug absorption?

5. Explain Fick's law of diffusion.

6. Describe the effect of ionization, protein binding and pH on drug distribution.

7. What is the effect of pregnancy and renal failure on drug distribution?

8. Differentiate free vs. bound form of drugs.

9. How to calculate cardiac output?

10. What are the components of whole blood?

11. Describe distribution of water in various body compartments.

Reference no: EM133565002

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