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Assignment:
Practice case study
An otherwise healthy infant developed a seizure 5 days post-birth. The mother and baby returned to the hospital for evaluation. Upon examination of the infant, the physician found that the baby demonstrated chorioretinitis. Prescreening of the mother during the third trimester of pregnancy did not demonstrate the presence of antibodies against T. gondii. At the time, she was advised to refrain from cleaning the litter boxes of the family's two cats. Upon questioning, the mother stated that she had been cleaning the litter boxes when other family members failed to do so. The physician suspected that the child may have congenital toxoplasmosis. Serological testing of the mother and the fetus gave the following results:
Anti-T. gondii IgM
Anti-T. gondii IgG
Mother
1:256
1:512
Baby
Not done
1. Did the mom get infected while being pregnant? How?
2. Evaluate the baby's status related to T. gondii infection?
3. What additional testing should be performed to confirm the baby's status?
4. How can infection with T. gondii during pregnancy be avoided?
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