Diagram of egfr signaling in cancer cell proliferation

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Deregulated epidermal growth factor (EGF) signaling has been implicated in diverse cancer types including colon and breast cancer. As such, ongoing efforts are focused on developing therapeutic agents targeting the pathway.

a. Draw a pathway diagram of EGFR signaling in cancer cell proliferation AND migration.

b. List one key mutation (amino acid changes) in EGFR, k-RAS, and b-RAF that are prevalent in cancer.

c. Discuss the functional consequences of each mutation in 1b.

Reference no: EM132666596

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