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Developmental Genetics1. What is the process of development?2. What are the 3 stages of Drosophila development?3. How does the gene “dorsal” cause the dorsal-ventral axes to form? What protein does the gene dorsal encode? What does it mean that dorsal is of maternal origin?4. How do bicoid and hunchback determine the anterior-posterior axis?5. What do homeotic genes do? How is the order of homeotic gene expression determined? Identify a set of homeotic genes shared by all vertebrates.6. How is apoptosis a critical part of development?7. Define: Totipotent , morphogens, caspases8. What do all cancers have in common?9. Why is a tumor defined as a clonal line of cells?10. What are the 3 classifications for a tumor?
You've developed a new Alzheimer's drug that disrupts the abnormal amyloid pathway that results in Alzheimer's disease. In its current formulation, the octanol/water partition coefficient of your drug is quite low, completely lipophobic. Why won't..
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Pleiotropy, and genetic heterogeneity can affect the severity of a disease in a family
Histone hyperacetylation of certain genes is associated with cancer. What is the effect of histone acetylation on gene expression, and what is the normal function of the genes affected?
why DNA was discarded as a possible candiate
Why is the maintenance of homeostasis especially important during development of new humans within the bodies of their mothers? What can go wrong if specific homeostatic functions are disrupted?
Why did the "RNA World" hypothesis have to await the discovery of ribozymes in order to become a widely attractive scenario?
How do monogenic human diseases compare and contrast to monohybrid Mendelian genetics?
a bacterium will construct different proteins to metabolize the sugars lactose or glucose, depending on which one it detects in the outside environment. What part of the bacterium allows it to recognize different substances in the outside environm..
question 1 protocols are important in medicine. we use them anytime that a particularly important process needs to be
Wild type Arabidopsis is a selfing diploid plant with 2n=10. You notice five different varieties with distinct phenotypes that involve leaves and fruit of abnormal size, shape and color. These mutations do not breed true and have odd segregation p..
Assume that you have conducted a study of a food borne outbreak that occurred recently at the "Road Kill Bar and Grill" First, explain which type of epidemiologic study design you would have been most likely to have used
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