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You have developed a keen interest in the adaptive immune system and plan on dedicating your scientific career to the study of this elegant system! As a first step, you take an immunology class, in which you learn about several aspects of the immune system. One, the process of signaling through receptors of the adaptive immune system, is of particular interest.What is the structure of the complete TCR and BCR? (in addition to text, you may use your own drawings if that is helpful)Describe, in detail, the signaling response to antigen recognition by the BCR.Describe, in detail, the signaling response to antigen recognition by the TCR.
Furthermore, you become interested in lymphocyte development. Please describe the processes surrounding the development of lymphocytes.Trace the development of B cells. Be sure to include at least six distinct stages, the key molecules, events, and locations of each.How is B cell development altered in the absence of Kit? B220? Overexpression of IL-7 receptor?Trace the development of T cells. Be sure to include at least six distinct stages, the key molecules, events, and locations of each.How is T cell development altered in the absence of ZAP-70? RAG-1/RAG-2? GATA-3?
About twice a year, one or two more birds from the neighbouring island arrive. What result do these new arrivals have. There are questions that follow the case study and the first one says to define the bold words from the case study in APA format. I..
Experiments with erythrocyte "ghosts" were carried out to learn more about the glucose transporter in red blood cells. "Ghosts" are prepared by lysing red blood cells in a hypotonic medium and washing away the cytoplasmic contents.
List two types of macromolecules that have been partially digested by the time acid chime moves into the intestine. Where did the digestion take place, and what enzymes were involved.
Albinism is a condition that results from the lack of normal pigmentation. In humans, individuals with two recessive alleles at ALBINO (aa) locus are albino.
About 5 percent of individuals with Down syndrome have a chromosomal translocation in which a third copy of chromosome 21 is attached to chromosome 14. If this translocation occurred in a parent's gonad, how can it lead to Down syndrome in a child.
The science of ecology has roots in many disciplines. Describe how nineteenth century naturalist influenced the development of ecology.
Consider a transmembrane protein complex that forms a hydrophilic pore across the plasma membrane of a eukaryotic cell. The pore is made of five similar protein subunits, each of which contributes a membrane-spanning alpha-helix to form the pore.
Find a virus capsid containing vimentin, your protein of interest, gets into the cell nucleus and is broken down with the DNA being released.
Discuss how would the pH and dissolved oxygen change over the course of a day (morning, noon, and night)? Over the course of a year? What is driving these changes?
Demonstrate that the overall process is equivalent to an isothermal expansion of the gas at T from V to 3V, where V is the original volume and Derive an express for dS for the overall process.
Early formulations of this medium used a smaller amount of carbohydrate and occasionally prodused false alkaline result after 48 hours. Why do you think this happened.
Determine what is the currently accepted scientific explanation for anthropogenic global climate change?
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