Determine the significance of the observation

Assignment Help Biology

Reference no: EM1381637

Question: Determine the significance of the observation that knocking out MyD88abrogates increases in Factor B and C3a but knocking out of TRIF does not? Describe in molecular terms.

Question: From these experiments can you determine the types of pathogens that caused sepsis in these mice? What are the most likely activating TLR ligand(s)? Explain and justify your answers to these two questions.

Question: What do these results suggest about the role of complement in septic shock? Which complement pathway is involved and at what step(s) of complement activation is regulation by TLR having its effect? Identify the key molecules and cells in the septic inflammatory response that are affected by complement activation and explain their role in sepsis.

Question: Why are C3a and Ba still present in sera from MyD88^-/- mice?

Question: Why is it that the researchers cannot measure C3b in sera from the sepsis-induced mice?

Reference no: EM1381637

Questions Cloud

Determine total hours committed by employee : Assume the weekly hours for all employees are stored in the two-dimensional array. Each row records the employee's seven-day work hours with seven columns. Determine total hours committed by each employee every week.

Community changes and development : How has your home community (pick any Indian city, town, or neighborhood where you grew up) changed since you were a child? Have there been significant changes in the community's economic base and in its racial and ethnic profile?

Optimal production run quantity : The Ambrosia Bakery makes cakes for freezing and subsequent sale. The bakery, which operates five days a week, 52 weeks a year, can produce cakes at the rate of 116 cakes per day. Optimal production run quantity

Development of the american court systems : Discuss in depth the development of the American Court Systems. Book is With justice for all? Nature of the American Legal System by Michael Fowler.

Determine the significance of the observation : Determine the significance of the observation that knocking out MyD88 abrogates increases in Factor B and C3a but knocking out of TRIF does not ? Describe in molecular terms.

A greater percentage of raw material purchases : A greater percentage of raw material purchases are paid with credit. More finished goods are produced for inventory instead of for order.

Explaining the drug-crime relationship : How do radical theorists explain the drug-crime relationship, and what do they advocate for? Is there any evidence supporting the effectiveness of what they advocate for (either domestically, internationally, or both)?

Significant factors contributing to mmcc-s success : Write down most significant factors contributing to MMCC's success with its new, secure, self-managed network? Describe the reasons for your choices.

Us nationalism and politics of fear : How is nationalism expressed in the United States and other parts of the world? Who benefits and who loses when nationalism is used as a justification for military interventions such as the War in Iraq?

User Account

All Pages